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Pifithrin-α Hydrobromide, 10 MG

Price$ 118.21
  • SKU: P-1177-10MG
  • Pack Size: 10 MG
Quantity
-
+

63208-82-2

367.3

C16H18N2OS • HBr

Soluble in DMSO, DMF, Methanol

-20°C


Description

Pifithrin-α Hydrobromide is a chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. It reversibly blocks p53 dependent transcriptional activation and apoptosis.

References

p53 Mediates Nontranscriptional Cell Death in Dopaminergic Cells in Response to Proteasome Inhibition
p53 Down-Regulates Phosphatase and Tensin Homologue Deleted on Chromosome 10 Protein Stability Partially through Caspase-Mediated Degradation in Cells with Proteasome Dysfunction
Histone Deacetylase Inhibitor-Mediated Radiosensitization of Human Cancer Cells: Class Differences and the Potential Influence of p53
Early Single Cell Bifurcation of Pro- and Antiapoptotic States during Oxidative Stress

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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