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Pifithrin-μ, 10 MG

Price$ 106.14
  • SKU: P-2723-10MG
  • Pack Size: 10 MG






Pifithrin-μ is a cell-permeable sulfonamide inhibitor of p53 binding and an anti-apoptotic. Direct inhibition of p53 binding to mitochondria as well as to Bcl-xL and Bcl-2 proteins by Pifithrin-μ has been observed. Pifithrin-μ selectively inhibits p53 translocation to mitochondria without affecting the transactivation function of p53.

Pifithrin-μ has been shown to reduce γ-radiation induced cell death in vitro. Unlike pifithrin-α (sc-45050), pifithrin-μ targets only the mitochondrial branch of the p53 pathway without affecting the important transcriptional functions of p53. Pifithrin-μ selectively inhibits HSP 70 (heat shock protein 70) activity.

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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