Soluble in DMSO and H2O
Potent inhibitor of PARP-1 and PARP-2 (potency 5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radio-potentiation. Does not show inherent cytotoxicity and shows no single agent activity in tumor models.
Research or further manufacturing use only, not for food or drug use.