4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone; AZD 2281; Ku-0059436
Cell-permeable. A highly potent and selective PARP-inhibitor with ICvalues of 5 nM and 1 nM for PARP-1 and PARP-2, respectively. Olaparib displays standalone activity in BRCA-1 deficient breast cancer cells.
Research or further manufacturing use only, not for food or drug use.