BR-1; P0108; Phosphatase of Regenerating Liver 3 Inhibitor; PTP4A3 Inhibitor; 5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone
PRL-3 Inhibitor is a potent inhibitor of phosphatase of regenerating liver-3 (PRL-3), IC50=0.9 mM1. Reduces the invasive properties of mouse melanoma B16F10 cells in a cellular model. Sensitizes PRL-3-expressing cancer cells to chemotherapeutics. Inhibits dephosphorylation of tyrosine-783 of integrin b1 in BGC823 and SW480 cells.
Research or further manufacturing use only, not for food or drug use.