166981-13-1 (free base)
Soluble in DMSO (up to 25 mg/ml).
CT-2584 (166981-13-1; free base) is a cytotoxic agent that alters phospholipid biosynthesis via inhibition of CTP (choline-phosphate cytidylyltransferase) causing an increase in phosphatidylinositol will decreasing levels of phosphatidylcholine. The altered phospholipid metabolism caused by CT-2584 results in a loss of lamellar structure and membrane integrity (especially in mitochondria and endoplasmic reticulum). CT-2584 was active against a wide range of tumor cell lines including multi-drug resistant lines.
Research or further manufacturing use only, not for food or drug use.