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Camostat mesilate, 10 MG

Price$ 42.35
  • SKU: C-2200-10MG
  • Pack Size: 10 MG
Quantity
-
+

59721-29-8

494.5 Da

C20H22N4O5 • CH3SO3H

May be dissolved in DMSO (50 mg/mL) or Water (50 mg/mL)

-20°C


Description

A serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis1 . Reduces weight gain and improves metabolism in obese rodent models2 . In clinical use (in Japan) for pancreatitis3 . Inhibits influenza virus replication in human tracheal epithelial cells4 . Reduces infection of Calu-3 lung cells by SARS-CoV-2 (responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming5 .

Shown to be effective against coronavirus.

  

References

• Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity

• Intestinal serine protease inhibition increases FGF21 and improves metabolism in obese mice

• The Serine Protease Inhibitor Camostat Mesilate Attenuates the Progression of Chronic Kidney Disease through its Antioxidant Effects

• The serine protease inhibitor camostat inhibits influenza virus replication and cytokine production in primary cultures of human tracheal epithelial cells

• SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

  

Not for human therapeutic use or for medicinal purposes. For research applications only.

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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