Soluble in Chloroform or DMSO. Moderately Soluble in Water.
Synthetic. Highly specific, cell permeable, and irreversible 20S proteasome inhibitor. It is believed lactacystin acts as a precursor for clasto-lactacystin b-lactone. Parkin Directly Modulates 26S Proteasome Activity.ASK1 Negatively Regulates the 26 S Proteasome.Parkin Ubiquitinates and Promotes the Degradation of RanBP2.Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3.
Research or further manufacturing use only, not for food or drug use.