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clasto-Lactacystin β-lactone, Synthetic, 100 UG

Price$ 247.23
  • SKU: L-1055-100UG
  • Pack Size: 100 UG
Quantity
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+

155975-72-7

213.2

C10H15NO4

Soluble in Chloroform or DMSO. Moderately Soluble in Water.

-20°C


Synthetic. Highly specific, cell permeable, and irreversible 20S proteasome inhibitor. It is believed lactacystin acts as a precursor for clasto-lactacystin b-lactone. Parkin Directly Modulates 26S Proteasome Activity.ASK1 Negatively Regulates the 26 S Proteasome.Parkin Ubiquitinates and Promotes the Degradation of RanBP2.Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3.

 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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