Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml); insoluble in water.
HMG-CoA reductase inhibitor. Simvastatin inhibits the biosynthesis of isoprenoids and prevents small G protein activation. Displays lipid lowering and antihypertensive effects. Displays antiinflammatory, immunomodulatory effects as well as protective effects in experimental traumatic brain injury. Activates Rac1-dependent signaling pathway.Simvastatin Induces Heme Oxygenase-1: A Novel Mechanism of Vessel Protection.
Research or further manufacturing use only, not for food or drug use.