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6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide, 10 MG

Price$ 166.78
  • SKU: S-2432-10MG
  • Pack Size: 10 MG




Soluble in DMSO (20 mg/ml)


A potent SIRT1 inhibitor (IC= 38 nM). EX-527 is 200-500-fold more selective for SIRT1 than for SIRT2 or SIRT3. Does not inhibit SIRT4-7, does not inhibit class I/II HDAC activity at concentrations up to 100M. Enhances p53 acetylation in response to DNA damaging agents.

0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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