49843-98-3
248.7
C13H13ClN2O
Soluble in DMSO (10mg/ml).
-20°C
Specific cell permeable inhibitor. Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC=98nM in vivo / IC=38nM in vitro; compared to hSIRT2: IC=19M and hSIRT3: IC=48M) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC100g). Inhibits the deacetylation of p53 (IC=1M).
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
