Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol.
Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives, isolated from Streptomyces. Chrysomycin A, with a vinyl group in the 8-position, is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. Chrysomyin A has a potent antibacterial, antifungal, antiviral and antitumor profile. More recent research on related metabolites, the gilvocarcins, suggests that chrysomycins may act as photoactivated crosslinkers of DNA to histones.
Research or further manufacturing use only, not for food or drug use.