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ABT-869, 1 MG

Price$ 355.78
  • SKU: A-2177-1MG
  • Pack Size: 1 MG
Quantity
-
+

796967-16-3

375.41

C21H18FN5O

DMSO

-20°C


ABT-869 is multi-targeted inhibitor of all members of the VEGF and PDGF receptor families (e.g., KDR, ICvalue of 4 nM), but has much less activity (ICvalues >1 M) against unrelated receptor tyrosine kinases, soluble tyrosine kinases or serine/threonine kinases. The kinase inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation (ICvalues of 2, 4 and 7 nM for PDGFR, KDR and CSF-1R, respectively) and VEGF-stimulated proliferation (0.2 nM ICfor human endothelial cells).

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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