AG-1498; Tyrphostin SU 1498
168835-82-3
390.5
C25H30N2O2
DMF, DMSO, Ethanol
-20°C
SU 1498 is a potent and selective inhibitor (IC= 700 nM) of vascular endothelial growth factor receptor 2 (VEGFR 2) (also known as Flk1). Very weak inhibitor of PDGFR-kinase (IC50 M), EGFR-kinase (IC100 M)and HER-2 kinase (IC100 M). SU1498 has been shown to cause accumulation of phosphorylated ERK and inhibits its activity in vivo and in vitro by inhibition of ERK dephosphorylation.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
