443913-73-3
475.35
C22H24BrFN4O2
DMSO (30 mg/ml) or EtOH (10 mg/ml)
-20°C
A potent inhibitor of kinase insert domain-containing receptor [KDR/vascular endothelial growth factor receptor (VEGFR) 2] tyrosine kinase activity (IC= 40 nM). This compound also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC= 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC= 500 nM) but shows selectivity relating to a range of other tyrosine and serine-threonine kinases.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
