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VEGFR2 Kinase Inhibitor I

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  • SKU: V-1082
  • Pack Size: 1 g
VEGFR2 Kinase Inhibitor I




Soluble in DMSO (10 mg/ml) or Etahnol (1 mg/ml)


Synonym: (Z)-3-[(2,4-Dimethyl-3-(ethoxycarbonyl)pyrrol-5-yl)methylidenyl]indolin-2-one

A highly selective, cell-permeable indolin-2-one class of receptor tyrosine kinase (RTK) inhibitor (IC = 70 nM) for murine vascular endothelial growth factor receptor 2 (VEGF-R2; KDR/Flk-1). The inhibition is suggested to be competitive with respect to ATP. Does not inhibit PDGFR, EGFR, and IGF-1 tyrosine kinase activities (IC 100 M).

0.1 lbs

Research or further manufacturing use only, not for food or drug use.

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