Bortezomib

SKU
P-2408
  • CAS:179324-69-7
  • Formula:C19H25BN4O4
  • MW:384.24
  • Appearance:White to off-white Solid
  • Purity:99% by HPLC
Product Name Qty
Bortezomib
1 mg
$61.42
Bortezomib
5 mg
$212.19

A potent (K = 0.6 nM), specific and reversible proteasome inhibitor. It inhibits cell proliferation of H460 cells (Human non-small cell lung cancer cell lines) with an ICof 0.1 M.

More Information
Alternate Name/Synonyms
MG-341; ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid;PS-341
SKU
P-2408
CAS #
179324-69-7
Chemical Name
MG-341; ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
Chemical Formula
C19H25BN4O4
Molecular Weight
384.24
Appearance
White to off-white Solid
Purity
99% by HPLC
Solubility
DMSO (200mg/ml) or EtOH (200 mg/ml)
Melting Point
139-143 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Bortezomib is a selective and robust 26S proteasome inhibitor, that is a boronic acid dipeptide derivative use in cancer
MDL NUMBER
MFCD09056737
CHEMACX
X1511968-5
INCHI
InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1
SMILES
B([C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c2cnccn2)(O)O
RTECS
ED7771666
UN #'S
UN 3249
PACKING GROUP
II
Handling
Protect from moisture and light
Certificate of Analysis 1
Certificate of Analysis 2
Handling Protect from moisture and light
UN #'S UN 3249
Packing Group II
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