PS48

SKU
P-1709
  • CAS:1180676-32-7
  • Formula:C17H15ClO2
  • MW:286.75
  • Appearance:White to off-white solid
  • Purity:≥95% by HPLC

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Product Name Qty
PS48
5 mg
$88.30
PS48
25 mg
$331.12
PS48
100 mg
$1,004.41

An allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd =10.3 μM).  Binds exlusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site.  It has recently been found that a combination of PS48, sodium butyrate (Cat. No. 1609-1000), a histone deacetylase inhibitor and the gene Oct-4, could enhance the reprogramming efficiency of keratinocytes isolated from human skin or hair follicles over 25-fold.

More Information
SKU
P-1709
CAS #
1180676-32-7
Chemical Name
(2Z)-5-(4-Chlorophenyl-3-phenyl-2-pentenoic acid
Chemical Formula
C17H15ClO2
Molecular Weight
286.75
Appearance
White to off-white solid
Purity
≥95% by HPLC
Solubility
DMSO (100 mM) or EtOH (50 mM)
Storage Temp
Store at -20°C
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