PS48
SKU
P-1709
- CAS:1180676-32-7
- Formula:C17H15ClO2
- MW:286.75
- Appearance:White to off-white solid
- Purity:≥95% by HPLC
SDS
CofA
An allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd =10.3 μM). Binds exlusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. It has recently been found that a combination of PS48, sodium butyrate (Cat. No. 1609-1000), a histone deacetylase inhibitor and the gene Oct-4, could enhance the reprogramming efficiency of keratinocytes isolated from human skin or hair follicles over 25-fold.
More Information
SKU
P-1709
CAS #
1180676-32-7
Chemical Name
(2Z)-5-(4-Chlorophenyl-3-phenyl-2-pentenoic acid
Chemical Formula
C17H15ClO2
Molecular Weight
286.75
Appearance
White to off-white solid
Purity
≥95% by HPLC
Solubility
DMSO (100 mM) or EtOH (50 mM)
Storage Temp
Store at -20°C