Psicofuranine

SKU
P-2423
  • CAS:1874-54-0
  • Formula:C11H15N5O5
  • MW:297.3
  • Appearance:White to off-white solid
  • Purity:≥98% (HPLC)
Product Name Qty
Psicofuranine
1 mg
$89.34
Psicofuranine
5 mg
$357.36

Psicofuranine is a nucleoside antibiotic isolated from Streptomyces sp. S 2113.

The mechanism of action of psicofuranine was studied by quantitative reversal of its antimicrobial action on Staphylococcus aureus. The inhibition can be effectively reversed by several compounds containing purine bases. The most effective reversing agents contained guanine, whereas adenine- and hypoxanthine-containing nucleosides and nucleotides were much less active. 

The effects of the antitumor agent, psicofuranine, have been investigated in rats. Longer treatment produced significant decreases in phosphate uptake by host tissues. 

Pscifuranine is antimetabolite of the purine biosynthesis and inhibits xanthosine monophosphate(XMP) aminase.

 

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More Information
Alternate Name/Synonyms
Angustmycin C, U-9586
SKU
P-2423
CAS #
1874-54-0
Chemical Name
9-½‚²-D-Psicofuranosyl-9H-purin-6-amine
Chemical Formula
C11H15N5O5
Molecular Weight
297.3
Appearance
White to off-white solid
Purity
≥98% (HPLC)
Solubility
Soluble in DMSO; poorly soluble in methanol
Stability
N/A
Storage Temp
-20°C
Merck Index
14: 7923
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