PX-866

SKU
P-2409
  • CAS:502632-66-8
  • Formula:C29H35NO8
  • MW:525.59
  • Appearance:Orange Solid
  • Purity:98% by TLC
Product Name Qty
PX-866
5 mg
$301.86
PX-866
1 mg
$74.04
Cell-permeable. A derivative of Wortmannin (Cat. No. 1670-1), that potently and irreversibly inhibits PI 3-kinase with selectivity for p110 (IC= 0.1 nM). Displays antitumor activity.
More Information
Alternate Name/Synonyms
DJM-166; DJM-2-166
SKU
P-2409
CAS #
502632-66-8
Chemical Name
(4S,4AR,5R,6AS,9AR,E)-1-((DIALLYLAMINO)METHYLENE)-11-HYDROXY-4-(METHOXYMETHYL)-4A,6A-DIMETHYL-2,7,10-TRIOXO-1,2,4,4A,5,6,6A,7,8,9,9A,10-DODECAHYDROINDENO[4,5-H]ISOCHROMEN-5-YL ACETATE
Chemical Formula
C29H35NO8
Molecular Weight
525.59
Appearance
Orange Solid
Purity
98% by TLC
Solubility
DMSO (~ 25 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
PX-866 inhibits tumor growth by blocking the PI 3-kinase pathway and cell motility
MDL NUMBER
MFCD07784511
CHEMACX
X1495745-0
INCHI
InChI=1S/C30H37NO7/c1-7-11-31(12-8-2)15-19-21(33)13-18(16-37-6)30(5)25(19)28(36)27(35)24-20-9-10-23(34)29(20,4)14-22(26(24)30)38-17(3)32/h7-8,15,18,20,22,36H,1-2,9-14,16H2,3-6H3/b19-15-/t18-,20+,22-,29+,30+/m1/s1
SMILES
CC(=O)O[C@@H]1C[C@]2([C@@H](CCC2=O)C3=C1[C@]4([C@H](CC(=O)/C(=C/N(CC=C)CC=C)/C4=C(C3=O)O)COC)C)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and air
Handling Protect from light and air
UN #'S Not Applicable
Packing Group Not Applicable
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