Pyridomycin

SKU
P-2803
  • CAS:18791-21-4
  • Formula:C27H32N4O8
  • MW:540.6
  • Appearance:Pink residue
  • Purity:>95% by HPLC
Product Name Qty
Pyridomycin
0.5 mg
$310.51
Pyridomycin
2.5 mg
$1,010.57
*Please inquire the availability for this product. Pyridomycin is a potent antibiotic active against mycobacteria and some Gram negative bacteria, originally isolated from Streptomyces abidoflavus by Umezawa group at the NIH Japan in 1953, and since isolated from different species and published under several names. The unusual 12-membered macrocyclic depsipeptide comprises three unique sub-units incorporating two substituted pyridines. Pyridomycin is thought to target NADH-dependent enoyl (acyl-carrier-protein) reductase InhA. Recent reports of activity against isoniazid-resistant mycobacteria has seen pyridomycin identified as a potential lead for new generation antibiotics.
More Information
Alternate Name/Synonyms
U24544, Antibiotic U24544, Erizomycin
SKU
P-2803
CAS #
18791-21-4
Chemical Formula
C27H32N4O8
Molecular Weight
540.6
Appearance
Pink residue
Purity
>95% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Pyridomycin is a potent antibiotic active against mycobacteria and some Gram negative bacteria
INCHI
InChI=1S/C27H32N4O8/c1-5-14(2)23-27(37)38-16(4)20(31-25(35)21-19(32)9-7-11-29-21)24(34)30-18(12-17-8-6-10-28-13-17)22(33)15(3)26(36)39-23/h6-11,13,15-16,18,20,22,32-33H,5,12H2,1-4H3,(H,30,34)(H,31,35)/b23-14-/t15-,16-,18+,20+,22+/m1/s1
SMILES
CC/C(=C\1/C(=O)O[C@@H]([C@@H](C(=O)N[C@H]([C@H]([C@H](C(=O)O1)C)O)Cc2cccnc2)NC(=O)c3c(cccn3)O)C)/C
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