QS11

SKU
Q-2411
  • CAS:944328-88-5
  • Formula:C36H33N5O2
  • MW:567.68
  • Appearance:White Solid
  • Purity:98% by HPLC
Product Name Qty
QS11
5 mg
$187.95
Inhibits the GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) as well as synergizes the Wnt/-catenin signaling pathway. The Wnt/-catenin signaling pathway regulates cell fate and behavior during embryogenesis, adult tissue homeostasis, and regeneration.
More Information
Alternate Name/Synonyms
(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol
SKU
Q-2411
CAS #
944328-88-5
Chemical Name
(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol
Chemical Formula
C36H33N5O2
Molecular Weight
567.68
Appearance
White Solid
Purity
98% by HPLC
Solubility
Soluble in DMSO (10 mg/ml)
Storage Temp
+4°C
THERAPEUTIC AREA
Oncological Disorders
USE
QS11 inhibits migration of ARFGAP overexpressing breast cancer cells
MDL NUMBER
MFCD18086864
CHEMACX
X2273893-4
INCHI
InChI=1S/C36H33N5O2/c42-23-31(20-25-8-3-1-4-9-25)38-34-33-35(40-36(39-34)43-32-19-18-28-12-7-13-30(28)21-32)41(24-37-33)22-26-14-16-29(17-15-26)27-10-5-2-6-11-27/h1-6,8-11,14-19,21,24,31,42H,7,12-13,20,22-23H2,(H,38,39,40)/t31-/m0/s1
SMILES
c1ccc(cc1)C[C@@H](CO)Nc2c3c(nc(n2)Oc4ccc5c(c4)CCC5)n(cn3)Cc6ccc(cc6)c7ccccc7
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and moisture
Handling Protect from air and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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