Questiomycin A

SKU
Q-2423
  • CAS:1916-59-2
  • Formula:C12H8N2O2
  • MW:212.2 Da
  • Appearance:Red to red brown solid
  • Purity:>98% by HPLC
Product Name Qty
Questiomycin A
1 mg
$113.02
Questiomycin A
5 mg
$396.19

Description

Questiomycin A is a phenoxazine produced by several Streptomyces species and some fungi and bacteria. Questiomycin A is weakly active against bacteria, fungi, plants and tumor cell lines, and inhibits aromatase and sulfatases. Questiomycin, like other phenoxazines, stimulates cell growth and turnover in vitro, an activity possibly related to their ability to form stable free radicals.

More recently, questiomycin A has been shown to inhibit pulmonary metastasis caused by mouse melanoma cells. Questiomycin A and related phenoxazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives.

More Information
Alternate Name/Synonyms
2-Amino-3H-phenoxazin-3-one; 2-Aminophenoxazone; AV Toxin C; NSC 94945; Isophenoxazine
SKU
Q-2423
CAS #
1916-59-2
Chemical Name
2-aminophenoxazin-3-one
Chemical Formula
C12H8N2O2
Molecular Weight
212.2 Da
Appearance
Red to red brown solid
Purity
>98% by HPLC
Solubility
Soluble in ethanol, methanol, DMF, or DMSO. Limited water solubility.
Melting Point
144.37 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Questiomycin A is weakly active against bacteria, fungi, plants and tumour cell lines
MDL NUMBER
MFCD00207317
INCHI
InChI=1S/C12H8N2O2/c13-7-5-9-12(6-10(7)15)16-11-4-2-1-3-8(11)14-9/h1-6H,13H2
SMILES
c1ccc2c(c1)nc-3cc(c(=O)cc3o2)N
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
Certificate of Analysis 1
HandlingAvoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
To Top