R-(-)-3-Quinuclidinol

SKU
Q-2419
  • CAS:25333-42-0
  • Formula:C7H13NO
  • MW:127.18
  • Appearance:White to off-white crystalline powder
  • Purity:<98%
Product Name Qty
R-(-)-3-Quinuclidinol
10 g
$849.88
R-(-)-3-Quinuclidinol
5 g
$491.16

 The two enantiomers of 3-quinuclidinol are frequently also known by other names, such as 3-hydroxyquinuclidine, 3-HQD and 1-Azabicyclo[2.2.2]octan-3-ol.

 
The quinuclidinol nucleus appears as a common pharmacophore in many ligands of muscarinic receptors (mAChR), of which there are five subtypes named M1-5. These are G protein-coupled acetylcholine receptors found in the plasma membranes of certain neurons and other cells, and are involved in diverse physiological functions such as smooth muscle contraction, exocrine and endocrine secretion, and nerve-to-nerve transmision. Radiolabelled derivatives of 3-quinuclidinyl benzilate (1), a non subtype-selective muscarinic receptor antagonist, are used in receptor binding assays and research into the roles of the individual receptors.
More Information
SKU
Q-2419
CAS #
25333-42-0
Chemical Name
(R)-(-)-3-Hydroxyquinuclidine, (R)-(-)-1-Azabicyclo[2.2.2]octan-3-ol
Chemical Formula
C7H13NO
Molecular Weight
127.18
Appearance
White to off-white crystalline powder
Purity
<98%
MDL NUMBER
MFCD13191732
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