Raf1 Kinase Inhibitor I

SKU
R-2020
  • Formula:C15H8Br2INO2
  • MW:520.9
  • Appearance:Dark orange Solid
  • Purity:97% by HPLC
Product Name Qty
Raf1 Kinase Inhibitor I
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$0.00

 A potent cRAF1 kinase inhibitor (IC = 9 nM). Shows 100-fold selectivity for Raf kinase versus Cdk1, Cdk2, c-src, ERK2, MEK, p38, Tie2, VEGFR2, and c-Fms. cRAF1 inhibitors are predicted to be broad spectrum antitumor agents.

More Information
SKU
R-2020
Chemical Formula
C15H8Br2INO2
Molecular Weight
520.9
Appearance
Dark orange Solid
Purity
97% by HPLC
Solubility
Soluble in DMSO (200 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Neurological Disorders
USE
An inhibitor of Raf-1 kinase and PMA-mediated activation of ERK1/2
MDL NUMBER
MFCD03453076
CHEMACX
X1342192-0
INCHI
InChI=1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)/b10-3+
SMILES
c1cc2c(cc1I)/C(=Cc3cc(c(c(c3)Br)O)Br)/C(=O)N2
Handling
Protect from Light Packaged under inert gas.
Handling Protect from Light Packaged under inert gas.
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