RepSox

SKU
R-2032
  • CAS:446859-33-2
  • Formula:C17H13N5
  • MW:287.32
  • Appearance:Off-White Solid
  • Purity:98% by HPLC
Product Name Qty
RepSox
25 mg
$329.44
RepSox
5 mg
$83.75
Cell-permeable. A TGE- type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC= 4nM). Can replace one of the four reprogramming factors Sox-2. RepSox has been successfully used in the direct reprogramming of mouse fibroblasts through induction of Nanog transcription.
More Information
Alternate Name/Synonyms
2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E616452
SKU
R-2032
CAS #
446859-33-2
Chemical Name
2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E616452
Chemical Formula
C17H13N5
Molecular Weight
287.32
Appearance
Off-White Solid
Purity
98% by HPLC
Solubility
Soluble in DMSO (20 mg/ml)
Stability
N/A
Storage Temp
Store at -20°C
THERAPEUTIC AREA
Not Available
USE
ALK5 Inhibitor II is a cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase
MDL NUMBER
MFCD09037561
CHEMACX
X1835302-5
INCHI
InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)
SMILES
Cc1cccc(n1)c2c(c[nH]n2)c3ccc4c(n3)cccn4
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
UN 2811
PACKING GROUP
III
HAZARD CLASS
Not Applicable
Handling
Do not take internally. Wear gloves and mask when handling the product.Avoid contact by all modes of exposure.
E-Guides
N/A
Blog Post
N/A
Certificate of Analysis 1
Promo text for AGS discount
N/A
Handling Do not take internally. Wear gloves and mask when handling the product.Avoid contact by all modes of exposure.
UN #'S UN 2811
Packing Group III
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