Retapamulin

SKU
R-2593
  • CAS:224452-66-8
  • Formula:C30H47NO4S
  • MW:517.8
  • Appearance:White solid
  • Purity:>99% by HPLC
Product Name Qty
Retapamulin
1 mg
$221.41
Retapamulin
5 mg
$773.74
*Please inquire the availability for this product. Retapamulin is a semi-synthetic pleuromutilin prepared by reacting pleuromutilin tosylate with tropine-3-thiol to give a more hydrophobic analogue with a tertiary amine. This enables formulation as a stable hydrochloride salt. Retapamulin is a broad spectrum antibiotic with no cross resistance to existing antibiotic classes, and is the first pleuromutilin approved for human use. Like all the pleuromutilins, retapamulin inhibits protein synthesis by binding to domain V of 23S rRNA.
More Information
Alternate Name/Synonyms
SB 275833
SKU
R-2593
CAS #
224452-66-8
Chemical Formula
C30H47NO4S
Molecular Weight
517.8
Appearance
White solid
Purity
>99% by HPLC
THERAPEUTIC AREA
Infectious Diseases
USE
Retapamulin is a broad spectrum antibiotic treating skin infection
MDL NUMBER
MFCD11045316
INCHI
InChI=1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22-,24-,26+,27+,28-,29+,30+/m1/s1
SMILES
C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CS[C@@H]4C[C@H]5CC[C@@H](C4)N5C)C
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