Reticulol

SKU
R-2595
  • CAS:26246-41-3
  • Formula:C11H10O5
  • MW:222.2
  • Appearance:White Powder
  • Purity:>95% by HPLC
Product Name Qty
Reticulol
1 mg
$235.39
Reticulol
5 mg
$822.67

*Please inquire the availability for this product. Reticulol is an isocoumarin metabolite produced by selected species of Streptomyces. Reticulol was first described as a potent inhibitor of cyclic nucleotide phosphodiesterase but more recent research has demonstrated a topoisomerase I inactivation mechanism. Reticulol also causes dose dependent inhibition of lung metastasis in the B16F10 melanoma model.

More Information
Alternate Name/Synonyms
6,8-Dihydroxy-7-methoxy-3-methylisocoumarin
SKU
R-2595
CAS #
26246-41-3
Chemical Name
6,8-Dihydroxy-7-methoxy-3-methylisocoumarin
Chemical Formula
C11H10O5
Molecular Weight
222.2
Appearance
White Powder
Purity
>95% by HPLC
Solubility
Soluble in water, methanol, DMSO, ethanol (moderate), and DMF
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Antitumor efficacy of reticulol against the lung metastasis model B16F10 melanoma
MDL NUMBER
MFCD11111617
CHEMACX
X2982835-5
INCHI
InChI=1S/C11H10O5/c1-5-3-6-4-7(12)10(15-2)9(13)8(6)11(14)16-5/h3-4,12-13H,1-2H3
SMILES
Cc1cc2cc(c(c(c2c(=O)o1)O)OC)O
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