Reveromycin A
SKU
R-1200
- CAS:134615-37-5
- Formula:C36H52O11
- MW:660.8
- Appearance:Tan Lyophilisate
- Purity:>99%

Epidermal Growth Factor Inhibitor. Inhibitor of the mitogenic activity of epidermal growth factor (EGF). A G1 phase cell cycle inhibitor displaying antiproliferative behavior against human cell lines KB and K562 as well as antifungal activity. RM-A Ind es Cell Death Specifically in OCs in Cell Cultures. RM-A Inhibits Bone Resorption in Vitro and in Vivo.1 Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Je-Tae Woo, Makoto Kawatani, et al, Mar 2006; 103: 4729 - 4734.
More Information
SKU
R-1200
CAS #
134615-37-5
Chemical Formula
C36H52O11
Molecular Weight
660.8
Appearance
Tan Lyophilisate
Purity
>99%
Solubility
Soluble in DMSO (83 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (~2 mg/ml), and DMF
Storage Temp
-20°C
Certificate of Analysis 1
Certificate of Analysis 2