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Reversine

SKU
R-2034
  • CAS:656820-32-5
  • Formula:C12H27N7O
  • MW:393.49
  • Appearance:Off-White Solid
  • Purity:98% by TLC

Starting at $51.27

Product Name Qty
Reversine
1 mg
$51.27
Reversine
5 mg
$179.97
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A cell-permeable, potent, and selective human A adenosine receptor antagonist (K= 0.66M) and an aurora kinase inhibitor (IC of 30-550 nM for blast colony formation assay). Induces dedifferentiation in murine C2C12 myoblasts. Thye cells were also shown to regain multipluripotency following removal of the compound.

More Information
Alternate Name/Synonyms
2-(4-Morpholinoanilino)-6-cyclohexylaminopurine
SKU
R-2034
CAS #
656820-32-5
Chemical Name
2-(4-Morpholinoanilino)-6-cyclohexylaminopurine
Chemical Formula
C12H27N7O
Molecular Weight
393.49
Appearance
Off-White Solid
Purity
98% by TLC
Solubility
Soluble in DMSO (~7-10 mg/ml)
Storage Temp
Store at -20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Reversine, a novel Aurora kinases inhibitor, inhibits colony formation of human acute myeloid leukemia cells
MDL NUMBER
MFCD09953189
CHEMACX
X1494446-8
INCHI
InChI=1S/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27)
SMILES
c1cc(ccc1Nc2nc3c(c(n2)NC4CCCCC4)nc[nH]3)N5CCOCC5
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Do not take internally. Wear gloves and mask when handling the product.Avoid contact by all modes of exposure.
Handling Do not take internally. Wear gloves and mask when handling the product.Avoid contact by all modes of exposure.
UN #'S Not Applicable
Packing Group Not Applicable
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