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RG-108

SKU
R-2030
  • CAS:48208-26-0
  • Formula:C19H14N2O4
  • MW:334.33
  • Appearance:Beige to yellow Solid
  • Purity:98% by HPLC
Product Name Qty
RG-108
10 mg
$131.00
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A DNA methyltransferase (DNMT) inhibitor. RG-108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294 (Cat. No. 1678-5), RG-108 enhances programming.
More Information
Alternate Name/Synonyms
N-Phthalyl-L-tryptophan
SKU
R-2030
CAS #
48208-26-0
Chemical Name
(2S)-2-(1,3-DIOXOISOINDOL-2-YL)-3-(1H-INDOL-3-YL)PROPANOIC ACID
Chemical Formula
C19H14N2O4
Molecular Weight
334.33
Appearance
Beige to yellow Solid
Purity
98% by HPLC
Solubility
Soluble in DMSO (10 mg/ml)
Storage Temp
Store at -20°C. Protect from air and light
THERAPEUTIC AREA
Oncological Disorders
USE
Anti-tumoral effect of the non-nucleoside DNMT inhibitor RG108 in human prostate cancer cells
MDL NUMBER
MFCD08705332
CHEMACX
X1544237-6
INCHI
InChI=1S/C19H14N2O4/c22-17-13-6-1-2-7-14(13)18(23)21(17)16(19(24)25)9-11-10-20-15-8-4-3-5-12(11)15/h1-8,10,16,20H,9H2,(H,24,25)/t16-/m0/s1
SMILES
c1ccc2c(c1)c(c[nH]2)C[C@@H](C(=O)O)N3C(=O)c4ccccc4C3=O
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Do not take internally. Wear gloves and mask when handling the product.Avoid contact by all modes of exposure.
Handling Do not take internally. Wear gloves and mask when handling the product.Avoid contact by all modes of exposure.
UN #'S Not Applicable
Packing Group Not Applicable
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