Ro 61-8048

SKU
R-2419
  • CAS:199666-03-0
  • Formula:C17H15N3O6S2
  • MW:421.45
  • Appearance:Off-White Solid
  • Purity:98% by HPLC
Product Name Qty
Ro 61-8048
25 mg
$404.38
Ro 61-8048
5 mg
$108.21
Cell-permeable. A high-affinity small molecule inhibitor of KMO (kynurenine 3-monoxygenase or kynurenine 3-hydroxylase)(K = 4.8 nM, IC= 37 nM).
More Information
Alternate Name/Synonyms
3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
SKU
R-2419
CAS #
199666-03-0
Chemical Name
3,4-Dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide
Chemical Formula
C17H15N3O6S2
Molecular Weight
421.45
Appearance
Off-White Solid
Purity
98% by HPLC
Solubility
DMSO (100 mM) or EtOH (10 mM)
Storage Temp
-20°C
THERAPEUTIC AREA
Neurological Disorders
USE
Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase (KMO) inhibitor in Huntington's disease
MDL NUMBER
MFCD11040807
CHEMACX
X1755810-6
INCHI
InChI=1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
SMILES
COc1ccc(cc1OC)S(=O)(=O)Nc2nc(cs2)c3cccc(c3)[N+](=O)[O-]
Peptide sequence
Not Applicable
RTECS
DB2047000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light
Handling Protect from light
UN #'S Not Applicable
Packing Group Not Applicable
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