Romidepsin, HDAC inhibitor

SKU
R-2655
  • CAS:128517-07-7
  • Formula:C24H36N4O6S2
  • MW:540.71
  • Appearance:Colorless waxy solid
  • Purity:98% by HPLC NMR (Conforms)
Product Name Qty
Romidepsin, HDAC inhibitor
1 mg
$218.40

Romidepsin (2-128517-07-7) is a potent and selective inhibitor of class I histone deacetylases (HDACs), IC50 = 36, 47, 510 and 14,000 nM for HDAC1, 2, 4 and HDAC6, respectively. Induces apoptosis in a variety of cell lines and displays antitumor activity in mouse models. Romidepsin was recently approved for clinical use in T-cell lymphoma.

More Information
Alternate Name/Synonyms
FK222, FR901228, Depsipeptide
SKU
R-2655
CAS #
128517-07-7
Chemical Formula
C24H36N4O6S2
Molecular Weight
540.71
Appearance
Colorless waxy solid
Purity
98% by HPLC NMR (Conforms)
Solubility
Soluble in DMSO (up to 10 mg/ml).
Stability
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Storage Temp
-20°
Hazard Image
Yes
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