Rosiglitazone Maleate

SKU
R-2575
  • CAS:155141-29-0
  • Formula:C18 H19 N3 O3 S . C4 H4 O4
  • MW:473.504
  • Appearance:Solid
Product Name Qty
Rosiglitazone Maleate
5 mg
$131.00

 PPARĪ³ agonist

More Information
SKU
R-2575
CAS #
155141-29-0
Chemical Formula
C18 H19 N3 O3 S . C4 H4 O4
Molecular Weight
473.504
Appearance
Solid
Solubility
Soluble in water (partly), ethanol (2 mg/ml at 25 °C), DMSO (100 mg/ml), DMF (~10 mg/ml), and methanol.
Melting Point
120-122 °C
Storage Temp
+4°C
THERAPEUTIC AREA
Endocrinological Disorders
USE
Rosiglitazone Maleate is an insulin sensitizer. Exhibits binding to PPAR?. This compound has the effect of lowering blood glucose as well as levels of insulin
MDL NUMBER
MFCD03427306
CHEMACX
X1406453-4
INCHI
InChI=1S/C18H19N3O3S.C4H4O4/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;5-3(6)1-2-4(7)8/h2-9,15H,10-12H2,1H3,(H,20,22,23);1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES
CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O
RTECS
XJ5813870
UN #'S
UN 3077
PACKING GROUP
III
Citations
SIGNAL TRANSDUCTION: FALDH Reverses the Deleterious Action of Oxidative Stress Induced by Lipid Peroxidation Product 4-Hydroxynonenal on Insulin Signaling in 3T3-L1 Adipocytes Damien Demozay, Jean-Christophe Mas, Stephane Rocchi, and Emmanuel Van Obberghen Diabetes, May 2008; 57: 1216 - 1226.
Citations_Hyperlink
http://diabetes.diabetesjournals.org/cgi/reprint/57/5/1216
UN #'S UN 3077
Packing Group III
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