SDS
CofA
Rubiginone D2, isolated from the strain of Streptomyces sp. (strain Gö N1/5) exhibit potential vincristine-induced cytotoxicity against multi-drug-resistant tumor cells.
Rubiginones feature the typical benz[a]anthraquinone structure of the angucyclinone antibiotics, a growing class of secondary metabolites with remarkable biological properties.
Product References
New biologically active rubiginones from Streptomyces sp., Puder C, et al, J Antibiot 53(4):329-36 (2000)
Chemical and biological properties of rubiginone, a complex of new antibiotics with vincristine-cytotoxicity potentiating activity., Oka M, et al, J Antibiot 43(8):967-76 (1990)
More Information
SKU
R-2474
CAS #
274913-71-2
Chemical Name
(2S,3S,4R)-2,4-Dihydroxy-8-methoxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione
Chemical Formula
C20H16O6
Molecular Weight
352.3
Appearance
Yellow solid with a green cast
Purity
≥98% (HPLC)
Solubility
Soluble in DMSO or acetone; slightly soluble in methanol
Storage Temp
-20°C
