RVX-208, BET bromodomain inhibitor

SKU
R-2657
  • CAS:1044870-39-4
  • Formula:C20H22N2O5
  • MW:370.41
  • Appearance:White solid
  • Purity:98% by TLC NMR (Conforms)
Product Name Qty
RVX-208, BET bromodomain inhibitor
25 mg
$284.65

RVX-208 (1044870-39-4) is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD1. RVX-208 increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo. Reduces atherosclerosis.

More Information
Alternate Name/Synonyms
Apabetalone
SKU
R-2657
CAS #
1044870-39-4
Chemical Name
2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinzolinone
Chemical Formula
C20H22N2O5
Molecular Weight
370.41
Appearance
White solid
Purity
98% by TLC NMR (Conforms)
Solubility
Soluble in DMSO (up to 75 mg/ml) or in Ethanol (up to 4 mg/ml).
Stability
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Storage Temp
-20°C (des.)
Hazard Image
Yes
Promo text for AGS discount
N/A
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