S-Trityl-L-cysteine

SKU
T-1186
  • CAS:2799-07-7
  • Formula:C22H21NO2S
  • MW:363.5
  • Appearance:White to off-white Solid
Product Name Qty
S-Trityl-L-cysteine
100 mg
$22.33
S-Trityl-L-cysteine
500 mg
$67.00
Potent, cell permeable cysteine thioether displaying anti-mitotic and anti-tumor properties. Inhibits mitosis by blocking basal and microtubule-activated ATPase activities of the mitotic kinesin Eg5 (IC50=1 uM and 140nm). Induces mitotic arrest in HeLa cells (IC50=700nM) and inhibits the growth of NCI tumor cell line panel (GI50=1.31 uM).
More Information
Alternate Name/Synonyms
Trityl-cysteine, NSC 83265
SKU
T-1186
CAS #
2799-07-7
Chemical Name
(2R)-2-AMINO-3-TRITYLSULFANYLPROPANOIC ACID
Chemical Formula
C22H21NO2S
Molecular Weight
363.5
Appearance
White to off-white Solid
Solubility
Soluble in DMSO
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
S-Trityl-L-cysteine is a cell-permeable cysteine thioether compound that exhibits antitumor and antimitotic properties by inhibiting mitotic kinesin Eg5
MDL NUMBER
MFCD00002611
CHEMACX
X1014343-0
INCHI
InChI=1S/C22H21NO2S/c23-20(21(24)25)16-26-22(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,20H,16,23H2,(H,24,25)/t20-/m0/s1
SMILES
c1ccc(cc1)C(c2ccccc2)(c3ccccc3)SC[C@@H](C(=O)O)N
RTECS
AY7710000
Handling
Store in Tightly Sealed Vial Caution: Harmful.
Promo text for AGS discount
N/A
Handling Store in Tightly Sealed Vial Caution: Harmful.
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