Salinosporamide A
SKU
S-3305
- CAS:437742-34-2
- Formula:C15H20ClNO4
- MW:313.8
- Appearance:White solid.
- Purity:≥95% (HPLC)

Salinosporamide A is a natural proteasome inhibitor. It is a β-lactone-γ-lactam that irreversibly inhibits all three protease activities within the proteasome (IC50s = 3.5, 28, and 430 nM for β5 (chymotrypsin), β2 (macropain), and β1 (C5) subunits, respectively), both in vitro and in vivo. 2,3Salinosporamide A has potential applications in cancer therapy, particularly in combination with other chemotherapeutics.
More Information
SKU
S-3305
CAS #
437742-34-2
Chemical Formula
C15H20ClNO4
Molecular Weight
313.8
Appearance
White solid.
Purity
≥95% (HPLC)
Solubility
Soluble in DMSO. Do not dissolve in methanol or ethanol.
Storage Temp
-20°C
Handling
KEEP UNDER INERT GAS. PROTECT FROM LIGHT and MOISTURE.
Hazard Image
Yes
Certificate of Analysis 1
Certificate of Analysis 2
Handling | KEEP UNDER INERT GAS. PROTECT FROM LIGHT and MOISTURE. |
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