Sancycline

SKU
S-2751
  • CAS:808-26-4
  • Formula:C21H22N2O7
  • MW:414.4
  • Appearance:Yellow to orange solid
  • Purity:>98% by HPLC
Product Name Qty
Sancycline
1 mg
$151.48
Sancycline
5 mg
$529.03
*Please inquire the availability for this product. Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin, first reported in 1962. As the simplest of the early tetracyclines, sancycline was the first to be totally synthesised by Conover and co-workers. Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.
More Information
Alternate Name/Synonyms
6-Demethyl-6-deoxytetracycline, Bonomycin, Norcycline
SKU
S-2751
CAS #
808-26-4
Chemical Formula
C21H22N2O7
Molecular Weight
414.4
Appearance
Yellow to orange solid
Purity
>98% by HPLC
Solubility
Soluble in ethanol, methanol, DMSO, DMF Limited water solubility
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Sancycline is a antibiotic
MDL NUMBER
MFCD00864992
INCHI
InChI=1S/C21H22N2O7/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29/h3-5,9-10,15,24,26-27,30H,6-7H2,1-2H3,(H2,22,29)/t9-,10-,15-,21-/m0/s1
SMILES
CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4cccc(c4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O
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