Sancycline hydrochloride

SKU
S-2753
  • CAS:6625-20-3
  • Formula:C21H23ClN2O7
  • MW:450.9
  • Appearance:Yellow to orange solid
  • Purity:>98% by HPLC
Product Name Qty
Sancycline hydrochloride
1 mg
$113.02
Sancycline hydrochloride
5 mg
$396.19
*Please inquire the availability for this product. Sancycline hydrochloride is the hydrochloride salt of a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin, first reported in 1962. As the simplest of the early tetracyclines, sancycline was the first to be totally synthesised by Conover and co-workers. Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.
More Information
Alternate Name/Synonyms
6-Demethyl-6-deoxytetracycline hydrochloride, NSC 51812
SKU
S-2753
CAS #
6625-20-3
Chemical Formula
C21H23ClN2O7
Molecular Weight
450.9
Appearance
Yellow to orange solid
Purity
>98% by HPLC
Solubility
Soluble in Methanol
Melting Point
224-2280°C
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Sancycline Hydrochloride is a semi-synthetic antibiotic
MDL NUMBER
MFCD09842560
INCHI
InChI=1S/C21H22N2O7.ClH/c1-23(2)15-10-7-9-6-8-4-3-5-11(24)12(8)16(25)13(9)18(27)21(10,30)19(28)14(17(15)26)20(22)29;/h3-5,9-10,15,24,26-27,30H,6-7H2,1-2H3,(H2,22,29);1H/t9-,10-,15-,21-;/m0./s1
SMILES
CN(C)[C@H]1[C@@H]2C[C@@H]3Cc4cccc(c4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O.Cl
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