- Appearance:Pale yellow Solid
- Purity:98% by HPLC
Cell-permeable. A potent inhibitior of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (Kd = 1.2 nM). Inhibits smoothened agonist effects with an ICof 20 nM in Shh-LIGHT2 cells. SANT-1 inhibits both wild type and oncogenic Smo with equal potency.
Pale yellow Solid
98% by HPLC
DMSO (~50 mM) or EtOH (~25 mM)
Store at -20°C. Protect from air and light.
A Smo inhibitor and Sonic Hedgehog signaling pathway antagonist use in cancer
Do not take internally. Wear gloves and mask wehn handling the product.Avoid contact by all modes of exposure.
|Handling||Do not take internally. Wear gloves and mask wehn handling the product.Avoid contact by all modes of exposure.|
|UN #'S||Not Applicable|
|Packing Group||Not Applicable|