SANT-2

SKU
S-2424
  • CAS:329196-48-7
  • Formula:C26H26ClN3O4
  • MW:479.96
  • Appearance:White to off-white Solid
  • Purity:95% by NMR
Product Name Qty
SANT-2
1 mg
$61.42
SANT-2
5 mg
$184.26
Cell-permeable. A potent antagonist of Hedgehog (Hh) signaling pathway. Antagonizes smoothened receptor activity (KD = 12 nM) and inhibits SAG (Cat. No. 1939-500,1000) activity. SANT-2 should be a useful tool to study the Hh signaling pathway.
More Information
Alternate Name/Synonyms
N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
SKU
S-2424
CAS #
329196-48-7
Chemical Name
N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
Chemical Formula
C26H26ClN3O4
Molecular Weight
479.96
Appearance
White to off-white Solid
Purity
95% by NMR
Solubility
DMSO (100 mM) or EtOH (100 mM)
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
An inhibitor of Smo (Hedgehog signaling pathway) and SAG
MDL NUMBER
MFCD01827636
CHEMACX
X1833192-1
INCHI
InChI=1S/C26H26ClN3O4/c1-4-32-22-13-16(14-23(33-5-2)24(22)34-6-3)26(31)28-17-11-12-19(27)18(15-17)25-29-20-9-7-8-10-21(20)30-25/h7-15H,4-6H2,1-3H3,(H,28,31)(H,29,30)
SMILES
CCOc1cc(cc(c1OCC)OCC)C(=O)Nc2ccc(c(c2)c3[nH]c4ccccc4n3)Cl
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light
E-Guides
N/A
Blog Post
N/A
Certificate of Analysis 1
Promo text for AGS discount
N/A
Handling Protect from light
UN #'S Not Applicable
Packing Group Not Applicable
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