Saracatinib

SKU
S-2425
  • CAS:379231-04-6
  • Formula:C27H32ClN5O5
  • MW:542.03
  • Appearance:Crystalline Solid
  • Purity:99% by HPLC
Product Name Qty
Saracatinib
5 mg
$301.86
Saracatinib
25 mg
$905.55
AZD0530 is a dually active inhibitor of c-Src and Bcr-ABL, on bone resorption. AZD0530 inhibited tumor growth in a manner independent of dose and inhibited phosphorylation of focal adhesion kinase (FAK) and paxillin in a dose-dependent manner in a Calu-6 Xenograft model.
More Information
Alternate Name/Synonyms
AZD-0530
SKU
S-2425
CAS #
379231-04-6
Chemical Name
N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYL-1-PIPERAZINYL)ETHOXY]-5-[(TETRAHYDRO-2H-PYRAN-4-YL)OXY]-4-QUINAZOLINAMINE
Chemical Formula
C27H32ClN5O5
Molecular Weight
542.03
Appearance
Crystalline Solid
Purity
99% by HPLC
Solubility
DMSO (~ 200 mg/ml) or EtOH (~ 200 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Saracatinib is a Src inhibitor use in cancer
MDL NUMBER
MFCD09832698
CHEMACX
X1722059-2
INCHI
InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)
SMILES
CN1CCN(CC1)CCOC2=CC3=C(C(=C2)OC4CCOCC4)C(=NC=N3)NC5=C(C=CC6=C5OCO6)Cl
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and moisture
Handling Protect from light and moisture
UN #'S Not Applicable
Packing Group Not Applicable
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