- Appearance:White to Off-White Solid
HMG-CoA reductase inhibitor. Simvastatin inhibits the biosynthesis of isoprenoids and prevents small G protein activation. Displays lipid lowering and antihypertensive effects. Displays antiinflammatory, immunomodulatory effects as well as protective effects in experimental traumatic brain injury. Activates Rac1-dependent signaling pathway.Simvastatin Induces Heme Oxygenase-1: A Novel Mechanism of Vessel Protection.
|Handling||Store in Tightly Sealed VialStable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.|
|UN #'S||UN 3077|