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Sinefungin

SKU
S-3349
  • CAS:58944-73-3
  • Formula:C15H23N7O5
  • MW:381.4 Da
  • Appearance:Tan solid
  • Purity:≥95%

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SDS
CofA
Product Name Qty
Sinefungin
5 mg
$315.00
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Description

Sinefungin is a nucleoside structurally related to S-adenosylhomocysteine and S-adenosylmethionine that was originally isolated from Streptomyces.1,2 While it has limited use as an antibiotic due to its high in vivo toxicity, sinefungin has proved useful as a non-selective inhibitor of SET domain-containing methyltransferases in the study of epigenetic regulation (IC50 values range from 0.1-20 μM).


Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Sinefunginum; A 9145; Antibiotic A 9145; Antibiotic 32232RP; RP 32232
SKU
S-3349
CAS #
58944-73-3
Chemical Name
6,9-diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-D-glycero-α-L-talo-decofuranuronic acid
Chemical Formula
C15H23N7O5
Molecular Weight
381.4 Da
Appearance
Tan solid
Purity
≥95%
Solubility
Water (up to 20 mg/mL)
Stability
Stable for 2 years as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.
Storage Temp
-20°C (des.)
THERAPEUTIC AREA
Antibiotic, Inhibitor
USE
Useful as a non-selective inhibitor of SET domain-containing methyltransferases in the study of epigenetic regulation
Handling
Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid prolonged or repeated exposure.
Hazard Image
Yes
msds 1
S-3349, Sinefungin, SDS, diamond format.pdf
Certificate of Analysis 1
S-3349, L1069.pdf
GHS PICTOGRAMS
Handling Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid prolonged or repeated exposure.
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