SirtAct, Sirt1 activator

SKU
S-3345
  • CAS:839699-72-8
  • Formula:C20H25N5O2
  • MW:367.46
  • Appearance:Olive green solid
  • Purity:98% by TLC NMR (Conforms)
Product Name Qty
SirtAct, Sirt1 activator
25 mg
$341.59

SirtAct (839699-72-8) is a Sirt1 activator (233% at 10 μM) Suppresses TNFα release from THP-1 cells and stimulates adipogenesis in 3T3L1 cells. SIRT1 stimulation by SirtAct leads to decreased tissue factor mediated thrombogenicity in mice. SirtAct inhibits NFκB activation and reduces inflammatory cytokine production in lamina propria mononuclear cells from IBD patients. Prevents and cures experimental colitis in a mouse model.

More Information
SKU
S-3345
CAS #
839699-72-8
Chemical Name
2-Amino-N-cyclopentyl-1-(3-methoxypropyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide
Chemical Formula
C20H25N5O2
Molecular Weight
367.46
Appearance
Olive green solid
Purity
98% by TLC NMR (Conforms)
Stability
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Storage Temp
-20°C (des.)
Hazard Image
Yes
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