Sitagliptin Phosphate Monohydrate

SKU
S-2435
  • CAS:654671-77-9
  • Formula:C16H15F6N5OH3PO4H2O
  • MW:523.32
  • Appearance:White Solid
  • Purity:98% by HPLC
Product Name Qty
Sitagliptin Phosphate Monohydrate
100 mg
$61.42
Sitagliptin Phosphate Monohydrate
1 g
$441.11
Sitagliptin is an anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Sitagliptin inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release. Sitagliptin stimulates the insulin release and lowers blood glucose.
More Information
Alternate Name/Synonyms
7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate; MK-0431
SKU
S-2435
CAS #
654671-77-9
Chemical Name
7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate; MK-0431
Chemical Formula
C16H15F6N5OH3PO4H2O
Molecular Weight
523.32
Appearance
White Solid
Purity
98% by HPLC
Solubility
Soluble in H2O
Stability
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Endocrinological Disorders
USE
A potent, orally active inhibitor of DPP-IV used in type 2 diabetes
MDL NUMBER
MFCD10001393
CHEMACX
X1611286-0
PubChecm ID
N/A
INCHI
InChI=1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1,2,3,4);1H2/t9-;;/m1../s1
SMILES
C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and moisture
Special Shipping
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Additional Images
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Structure Available (Y/N)
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Handling Protect from air and moisture
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Packing Group Not Applicable
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