Sorafenib (base)

SKU
S-2727
  • CAS:284461-73-0
  • Formula:C21 H16 Cl F3 N4 O3
  • MW:464.829
Product Name Qty
Sorafenib (base)
10 mg
$85.43

 Raf-1 inhibitor (and other kinases)

More Information
SKU
S-2727
CAS #
284461-73-0
Chemical Formula
C21 H16 Cl F3 N4 O3
Molecular Weight
464.829
Solubility
Soluble in DMSO (~20 mg/ml), Hot Methanol, DMF (~20 mg/ml), 1:2 solution of DMSO:PBS(PH 7.2 ) (~0.3 mg/ml), 100% ethanol, and ethyl acetate.
Melting Point
202.2-203.9 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Sorafenib is a RAF kinase inhibitor which suppresses ERK phosphorylation use in cancer
MDL NUMBER
MFCD06411450
CHEMACX
X1511955-8
INCHI
InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
SMILES
CNC(=O)c1cc(ccn1)Oc2ccc(cc2)NC(=O)Nc3ccc(c(c3)C(F)(F)F)Cl
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