SDS
CofA
Cell-permeable. A potent and selective inhibitor of Stat3 SH2 domain:pTyr interactions; also disrupts the binding of Stat3 to the IL-6R/gp130 peptide, GpYLPQTVNH2 and induces antitumor effects in vitro.
More Information
Alternate Name/Synonyms
FISKERERAILSTKPPGTFLLRFSESSK
SKU
S-2443
Chemical Name
FISKERERAILSTKPPGTFLLRFSESSK; H-PHE-ILE-SER-LYS-GLU-ARG-GLU-ARG-ALA-ILE-LEU-SER-THR-LYS-PRO-PRO-GLY-THR-PHE-LEU-LEU-ARG-PHE-SER-GLU-SER-SER-LYS-OH
Chemical Formula
C146H238N40O42.C2HF3O2
Molecular Weight
3225.74. 114.02
Appearance
Lyophilized Solid
Purity
95% by HPLC
Solubility
Soluble in H2O
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A potent and selective inhibitor of Stat3 SH2 domain:pTyr interactions; also disrupts the binding of Stat3 to the IL-6R/gp130 peptide, GpYLPQTVNH? and induces antitumor effects
MDL NUMBER
Not Available
CHEMACX
Not Applicable
INCHI
Not Applicable
SMILES
Not Applicable
Peptide sequence
H-PHE-ILE-SER-LYS-GLU-ARG-GLU-ARG-ALA-ILE-LEU-SER-THR-LYS-PRO-PRO-GLY-THR-PHE-LEU-LEU-ARG-PHE-SER-GLU-SER-SER-LYS-OH
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and moisture
| Handling | Protect from air and moisture |
|---|---|
| UN #'S | Not Applicable |
| Packing Group | Not Applicable |
